What are some of the changes you are hoping to see regarding special effects and/or additional damage modifiers? Personally, I think seeing much more dynamic visuals varying on the amount of damage dealt would be incredible. Or even better, visual effects that are dependant on the environment/enemy. For example, a lighting spell/weapon that had an improved visual effect if your were fighting a water based MOB along with the increased damage. It would be much more intersting than a number quickly flashing on the screen.
Secondly, I hope skillchains continue and develop even further in the new game. It was always fun being in a party that continually chained kills. Likely this will change with the rumors regarding smaller parties, but it's still a good option for teamwork. Share your thoughts!