Probably going to get bombed for this, but the use of synthasizer and over-ride guitar just is disappointing to me. For over twenty some years the vast majority of games have been forced to use electronic sounds and loops due to storage. Now we are at a point where you have an entire symphonic orchestra at your fingertips and we end up with something akin to Andrew Lloyd Webber.
I agree. The quality of the synthesized instruments is very impressive, but nothing beats the real thing. There's really no excuse to use midi-based music for games in this day and age. Heck, even Suikoden Tierkreis on DS has a full-fledged orchestra playing several of the songs from the soundtrack.