It doesn't really bother me. In fact, I enjoy the hustle and bustle. :)
But I have this thing where I always have to listen to the original soundtrack and the sound effects. It doesn't matter if I've played a game for years - I just have this need to experience the game as it was originally intended. If the music or sound effects are that obtrusive to me, then it won't lead me to adjust the volume but rather stop playing it altogether.
I also find myself humming little harmonies to complement the music. Like, all the time.
Please tell me I'm not alone. >.>
You are definitely not alone! Well, at least in the sense that if things sounded really annoying, it would be a huge deterrent to stop doing it, not to turn off the sound.
I personally absolutely love the sound of everyone working. The sounds are excellently done and it is really cool when people are succeeding all over the place. It is a pleasure to hear the :whishh: when a successful synth goes off. I would even go so far to say it makes me feel more concentrated and directed on my crafting.