First time I've been able to sit down and play since the update and I think the added item filtering (click body -> get body item only displayed).
I use a PS2 controller so I never touch the mouse and hardly ever the keyboard. I might be in the minority until PS3 release... but regardless, this change has allowed me to put off creating any macro's up to this point.
Not to mention the item stat info display. Really did help the UI. Does anyone hate it?