I can't speak for all of them, but here's my story. I've been leveling Blacksmith off Iron needles. So naturally I came to the point of clearing out my inventory. Upon starting to sell all the needles, at first I thought "Hey the new patch made this even smoother still!" then the shopkeeper froze. I could move the cursor but not actually sell anything or even back out of the menu. I could still speak to people around me and everything, but the shopkeeper would not respond causing me to have to force-quit the game. This has happened 4 times now.
So in summary. Do not sell too many things in one sitting, you will be forced to force-quit.
Just something for the SE dev. team to read and fix ^^