I do not macro due to the conditions when crafting being random. I would hate to miss a GOOD or EXCELLENT condition and cost me a possible HQ.
It's really a cost/benefit tradeoff. Is the effort saved when mass synthing worth the few missed good/excellent? Very often, it is for me.
I don't do it when I'm crafting finished goods, as I want all the quality I can get, but for mats, it definitely has its use.
As a real world example, I'm currently working on Chamomile Tea for CUL leves. No way am I going to craft each honey manually when I can use a macro and get 99% HQ synths. ****, I can even use macros on the tea if I'm willing to accept 85-90% HQ rate.
I'm not saying it should be used all the time, but don't discount macros completely.
One caveat: lag can wreak havoc with macros, causing actions to not fire if the cooldown hasn't registered. You''ll often need to pad your /waits or craft in a zone with lower population.
Yes this is the right idea. Manual for HQ important items > Macro for mass crafting of mid-level items that you want to still get decent exp for > Quick Synthesis for things that the EXP is not worth it when making 50 of.
As far as lag goes:
has worked for me in just about every location and time, with very little extra time (wasted) in between abilities.
I was checking last night and there are an ODD number of macro lines. So you can macro up to 8 abilities with 7 wait times.